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New insights into different surfactants’ impacts on sludge fermentation: Focusing on the particular metabolicprocesses and microbial genetic traits

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 8, doi: 10.1007/s11783-022-1527-6

Abstract:

• The promoting effects for VFA generation follow the order of APG>SDBS>HTAB.

Keywords： Waste activated sludge (WAS)     Volatile fatty acids (VFA)     Surfactant types     Functional microorganisms     Metabolic    

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Bidirectional Causality Between Immunoglobulin G N-Glycosylation and Metabolic Traits: A Mendelian Randomization Article

Xiaoni Meng, Weijie Cao, Di Liu, Isinta Maranga Elijah, Weijia Xing, Haifeng Hou, Xizhu Xu, Manshu Song, Youxin Wang

Engineering 2023, Volume 26, Issue 7,   Pages 74-88 doi: 10.1016/j.eng.2022.11.004

Abstract: traits.with GWAS results for metabolic traits (all P < 0.05).for IgG N-glycosylation traits, 72 (including one putatively causal metabolic trait for GP1 (high-densitytrait for GP3 (HDL-C) and one for GP9 (HDL-C)) genetically determined metabolic traits were found tometabolic traits.

Keywords： Mendelian randomization study     Immunoglobulin G     N-glycosylation     Metabolic traits     Quantitative trait    

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Genomic regions under selection for important traits in domestic horse breeds

Xuexue LIU, Yuehui MA, Lin JIANG

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 3,   Pages 289-294 doi: 10.15302/J-FASE-2017155

Abstract: Therefore, identification of genetic markers underlying the traits of interest in domestic horses is

Keywords： horse     coat color     racing performance     gait     height    

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Imaging technologies for plant high-throughput phenotyping: a review

Yong ZHANG, Naiqian ZHANG

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 4,   Pages 406-419 doi: 10.15302/J-FASE-2018242

Abstract:

Phenomics studies a variety of phenotypic plant traits and is the key to understanding genetic functionsrapid development of genomics, many plant phenotyping platforms have been developed to study complex traitsthese technologies in detecting and measuring plant morphological, physiological, and pathological traits

Keywords： high-throughput phenotyping     imaging technology     morphological traits     pathological traits     physiologicaltraits    

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Recent advances in understanding genetic variants associated with economically important traits in sheep

Song-Song XU, Meng-Hua LI

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 3,   Pages 279-288 doi: 10.15302/J-FASE-2017151

Abstract: However, genetic improvements for the key traits associated with meat, growth, milk, wool, reproductiontechnologies over the last decade, a list of functional genes and genetic variants associated with these traitsThis review covers recent genome-wide studies on sheep productive traits using high-throughput screeningcomprehensive information on functional genes and genetic variants associated with economically important traits

Keywords： sheep     high-throughput screening     productive traits     genome-wide studies    

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Effects of previous drying of sediment on root functional traits and rhizoperformance of emerged macrophytes

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 6, doi: 10.1007/s11783-021-1427-1

Abstract:

• Sediment desiccation alters morphological characteristics of aquatic sediment.

Keywords： Fibrous-root macrophytes     Thick-root macrophytes     Nutrients removal     Wet sediment     Dried-rewetted sediment    

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A genome-wide association study of five meat quality traits in Yorkshire pigs

Qian DONG,Huiying LIU,Xinyun LI,Wei WEI,Shuhong ZHAO,Jianhua CAO

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 2,   Pages 137-143 doi: 10.15302/J-FASE-2014014

Abstract: To identify genomic regions and haplotype blocks responsible for meat quality traits in pigs, a genome-wideassociation study was conducted for five traits including intramuscular fat content, pH at 45 min andtotal of 344 single nucleotide polymorphisms (SNP) were significantly associated with five meat quality traitsaddition, 25 haplotype blocks based on 116 SNPs were revealed with SNP combination patterns for five traitsOur study added new SNP information for identification of meat quality traits in pigs and will help elucidate

Keywords： Pig     GWAS     meat quality trait     SNP    

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Metabolic hypertension: concept and practice

Zhiming Zhu, Peijian Wang, Shuangtao Ma

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 201-206 doi: 10.1007/s11684-013-0264-4

Abstract: More than 60% of the risk factors for hypertension are associated with metabolic disturbances.Metabolic abnormalities increase the risk for hypertension and cause high blood pressure.Improving metabolic disturbances is beneficial for hypertension treatment.Due to the importance of metabolic abnormalities in the pathogenesis of hypertension, we propose a conceptof metabolic hypertension.

Keywords： hypertension     cardiometabolic risk factors     metabolic abnormalities    

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Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes

Jianping Ye

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 139-145 doi: 10.1007/s11684-015-0377-z

Abstract:

In obesity, chronic inflammation is believed to induce insulin resistance and impairs adipose tissue function. Although this view is supported by a large body of literature, it has been challenged by growing evidence that pro-inflammatory cytokines may favor insulin sensitivity through induction of energy expenditure. In this review article, interleukin 15 (IL-15) is used as a new example to explain the beneficial effects of the pro-inflammatory cytokines. IL-15 is secreted by multiple types of cells including macrophages, neutrophils and skeletal muscle cells. IL-15 expression is induced in immune cells by endotoxin and in muscle cells by physical exercise. Its transcription is induced by transcription factor NF-κB. IL-15 binds to its receptor that contains three different subunits (α, β and γ) to activate JAK/STAT, PI3K/Akt, IKK/NF-κB and JNK/AP1 pathways in cells. In the regulation of metabolism, IL-15 reduces weight gain without inhibiting food intake in rodents. IL-15 suppresses lipogenesis, stimulates brown fat function, improves insulin sensitivity through weight loss and energy expenditure. In human, circulating IL-15 is negatively associated with body weight. In the immune system, IL-15 stimulates proliferation and differentiation of T cells, NK cells, monocytes and neutrophils. In the anti-obesity effects of IL-15, T cells and NK cells are not required, but leptin receptor is required. In summary, evidence from human and rodents supports that the pro-inflammatory cytokine IL-15 may enhance energy expenditure to protect the body from obesity and type 2 diabetes. The mechanism of IL-15 action remains to be fully uncovered in the regulation of energy expenditure.

Keywords： inflammation     obesity     cytokine     energy expenditure     insulin resistance    

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electron transfer and its application in dictating routes of biochemical processes associated with metabolic

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 679-692 doi: 10.1007/s11684-021-0866-1

Abstract: Metabolic reprogramming, such as abnormal utilization of glucose, addiction to glutamine, and increasedelectron transfer (PET), which is used to characterize the degree of electron redistribution coupled with metabolicEnabling electron transfer could drive metabolic reprogramming in cancer metabolism.

Keywords： metabolic reprogramming     potential of electron transfer     cell proliferation     aerobic glycolysis     cancer    

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Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

Huating Li, Jing Zhang, Weiping Jia

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 25-30 doi: 10.1007/s11684-013-0244-8

Abstract: relevance of FGF21 in humans is still unclear, and the basis and consequences of increased FGF21 in metabolicpharmacological actions and physiological roles make FGF21 attractive drug candidates for treating metabolic

Keywords： FGF21     metabolism     pharmacology     physiology     clinical relevance    

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BULKED SEGREGANT RNA SEQUENCING (BSR-SEQ) IDENTIFIES A NOVEL ALLELE ASSOCIATED WITH WEEPING TRAITS IN

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 2,

Abstract: However, exploration of casual genes controlling weeping traits is rather limited.variation in the Pm024074 gene, providing precise marker-assisted breeding for weeping traits

Keywords： BSR-seq / PmUGT72B3 / Prunus mume / UDP-glycosyltransferase / weeping shoots / WGCNA    

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Metformin and metabolic diseases: a focus on hepatic aspects

Juan Zheng,Shih-Lung Woo,Xiang Hu,Rachel Botchlett,Lulu Chen,Yuqing Huo,Chaodong Wu

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 173-186 doi: 10.1007/s11684-015-0384-0

Abstract:

Metformin has been widely used as a first-line anti-diabetic medicine for the treatment of type 2 diabetes (T2D). As a drug that primarily targets the liver, metformin suppresses hepatic glucose production (HGP), serving as the main mechanism by which metformin improves hyperglycemia of T2D. Biochemically, metformin suppresses gluconeogenesis and stimulates glycolysis. Metformin also inhibits glycogenolysis, which is a pathway that critically contributes to elevated HGP. While generating beneficial effects on hyperglycemia, metformin also improves insulin resistance and corrects dyslipidemia in patients with T2D. These beneficial effects of metformin implicate a role for metformin in managing non-alcoholic fatty liver disease. As supported by the results from both human and animal studies, metformin improves hepatic steatosis and suppresses liver inflammation. Mechanistically, the beneficial effects of metformin on hepatic aspects are mediated through both adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways. In addition, metformin is generally safe and may also benefit patients with other chronic liver diseases.

Keywords： metformin     diabetes     hepatic steatosis     inflammatory response     insulin resistance    

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denitrification system with short-term pyridine exposure: Process capability, inhibition kinetics and metabolic

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 6, doi: 10.1007/s11783-021-1433-3

Abstract:

• Short-term effect of the pyridine exposure on the SAD process was investigated.

Keywords： Anammox     Inhibition     Metabolic pathway     Microbial community     Pyridine     SAD    

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Water-dispersible nano-pollutions reshape microbial metabolism in type-specific manners: A metabolic

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 9, doi: 10.1007/s11783-022-1548-1

Abstract:

• Water-dispersible nano-pollutions exhibit type-specific toxic effects on E. coli.

Keywords： Nano-toxicity     Nano-plastics     Quantum dots     Microbial metabolite     Metabolic dysregulation    

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Title Author Date Type Operation

New insights into different surfactants’ impacts on sludge fermentation: Focusing on the particular metabolicprocesses and microbial genetic traits

Journal Article

Bidirectional Causality Between Immunoglobulin G N-Glycosylation and Metabolic Traits: A Mendelian Randomization

Xiaoni Meng, Weijie Cao, Di Liu, Isinta Maranga Elijah, Weijia Xing, Haifeng Hou, Xizhu Xu, Manshu Song, Youxin Wang

Journal Article

Genomic regions under selection for important traits in domestic horse breeds

Xuexue LIU, Yuehui MA, Lin JIANG

Journal Article

Imaging technologies for plant high-throughput phenotyping: a review

Yong ZHANG, Naiqian ZHANG

Journal Article

Recent advances in understanding genetic variants associated with economically important traits in sheep

Song-Song XU, Meng-Hua LI

Journal Article

Effects of previous drying of sediment on root functional traits and rhizoperformance of emerged macrophytes

Journal Article

A genome-wide association study of five meat quality traits in Yorkshire pigs

Qian DONG,Huiying LIU,Xinyun LI,Wei WEI,Shuhong ZHAO,Jianhua CAO

Journal Article

Metabolic hypertension: concept and practice

Zhiming Zhu, Peijian Wang, Shuangtao Ma

Journal Article

Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes

Jianping Ye

Journal Article

electron transfer and its application in dictating routes of biochemical processes associated with metabolic

Journal Article

Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

Huating Li, Jing Zhang, Weiping Jia

Journal Article

BULKED SEGREGANT RNA SEQUENCING (BSR-SEQ) IDENTIFIES A NOVEL ALLELE ASSOCIATED WITH WEEPING TRAITS IN

Journal Article

Metformin and metabolic diseases: a focus on hepatic aspects

Juan Zheng,Shih-Lung Woo,Xiang Hu,Rachel Botchlett,Lulu Chen,Yuqing Huo,Chaodong Wu

Journal Article

denitrification system with short-term pyridine exposure: Process capability, inhibition kinetics and metabolic

Journal Article

Water-dispersible nano-pollutions reshape microbial metabolism in type-specific manners: A metabolic

Journal Article